47 research outputs found
Phononics: Manipulating heat flow with electronic analogs and beyond
The form of energy termed heat that typically derives from lattice
vibrations, i.e. the phonons, is usually considered as waste energy and,
moreover, deleterious to information processing. However, with this colloquium,
we attempt to rebut this common view: By use of tailored models we demonstrate
that phonons can be manipulated like electrons and photons can, thus enabling
controlled heat transport. Moreover, we explain that phonons can be put to
beneficial use to carry and process information. In a first part we present
ways to control heat transport and how to process information for physical
systems which are driven by a temperature bias. Particularly, we put forward
the toolkit of familiar electronic analogs for exercising phononics; i.e.
phononic devices which act as thermal diodes, thermal transistors, thermal
logic gates and thermal memories, etc.. These concepts are then put to work to
transport, control and rectify heat in physical realistic nanosystems by
devising practical designs of hybrid nanostructures that permit the operation
of functional phononic devices and, as well, report first experimental
realizations. Next, we discuss yet richer possibilities to manipulate heat flow
by use of time varying thermal bath temperatures or various other external
fields. These give rise to a plenty of intriguing phononic nonequilibrium
phenomena as for example the directed shuttling of heat, a geometrical phase
induced heat pumping, or the phonon Hall effect, that all may find its way into
operation with electronic analogs.Comment: 24 pages, 16 figures, modified title and revised, accepted for
publication in Rev. Mod. Phy
Emergency vaccination of rabies under limited resources – combating or containing?
BACKGROUND: Rabies is the most important viral zoonosis from a global perspective. Worldwide efforts to combat the disease by oral vaccination of reservoirs have managed to eradicate wildlife rabies in large areas of central Europe and North-America. Thus, repeated vaccination has been discontinued recently on a geographical scale. However, as rabies has not yet been eradicated globally, a serious risk of re-introduction remains. What is the best spatial design for an emergency vaccination program – particularly if resources are limited? Either, we treat a circular area around the detected case and run the risk of infected hosts leaving the limited control area, because a sufficient immunisation level has not yet been built up. Or, initially concentrate the SAME resources in order to establish a protective ring which is more distant from the infected local area, and which then holds out against the challenge of the approaching epidemic. METHODS: We developed a simulation model to contrast the two strategies for emergency vaccination. The spatial-explicit model is based on fox group home-ranges, which facilitates the simulation of rabies spread to larger areas relevant to management. We used individual-based fox groups to follow up the effects of vaccination in a detailed manner. Thus, regionally – bait distribution orientates itself to standard schemes of oral immunisation programs and locally – baits are assigned to individual foxes. RESULTS: Surprisingly, putting the controlled area ring-like around the outbreak does not outperform the circular area of the same size centred on the outbreak. Only during the very first baitings, does the ring area result in fewer breakouts. But then as rabies is eliminated within the circle area, the respective ring area fails, due to the non-controlled inner part. We attempt to take advantage of the initially fewer breakouts beyond the ring when applying a mixed strategy. Therefore, after a certain number of baitings, the area under control was increased for both strategies towards the same larger circular area. The circle-circle strategy still outperforms the ring-circle strategy and analysis of the spatial-temporal disease spread reveals why: improving control efficacy by means of a mixed strategy is impossible in the field, due to the build-up time of population immunity. CONCLUSION: For practical emergency management of a new outbreak of rabies, the ring-like application of oral vaccination is not a favourable strategy at all. Even if initial resources are substantially low and there is a serious risk of rabies cases outside the limited control area, our results suggest circular application instead of ring vaccination